To reduce the risk of experiencing side effects, the recommended initial adult dose of tizanidine is 2 mg up to 3 times daily. The dose is then increased gradually in 2 mg to 4 mg steps until an effective dose is reached. The most common maintenance dose is 8 mg taken up to 3 times daily (every 6 to 8 hours). Do not take more than 36 mg of tizanidine within a 24-hour period.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without talking to your doctor. Always take tizanidine exactly as prescribed by your doctor.
Tizanidine can be taken with or without meals, however taking tizanidine with food may increase the side effects of this medication. Always take tizanidine the same way, either with food or on an empty stomach.
Stopping the medication suddenly may cause an increase in blood pressure, rapid heart rate and muscle spasms. Talk to your doctor to find a safe way to stop taking the medication.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose of this medicine take it as soon as possible, if you remember within an hour or so of the missed dose. If you do not remember until later, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store tizanidine away from heat and direct light and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.